Diagnostic utility of procalcitonin as a biomarker

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April 2025
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Diagnostic utility of procalcitonin as a biomarker for late-onset neonatal sepsis

Background: To discover the diagnostic utility procalcitonin (PCT) as a biomarker for late-onset neonatal sepsis (Lons).


Strategies: The medical and laboratory knowledge from 131 sufferers within the neonatal neonatal intensive care unit (NICU) of our heart (Division of Neonatology, Renmin Hospital of Wuhan College) on June 1, 2015, to Could 31, 2018, have been retrospectively analyzed.

These sufferers have been divided into three teams primarily based on the situation of their illness: bacterial sepsis (BS) group (n = 47), sepsis mushrooms (FS) group (n = 39), and a gaggle of regular controls (n = 45, with out sepsis). blood tradition, routine blood exams, and testing for PCT protein and C-reactive (CRP) is carried out in all three teams. Each the PCT and CRP have been measured utilizing enzyme-linked immunosorbent assay (ELISA). blood cultures carried out in automated blood tradition system. Routine blood exams finished utilizing absolutely automated hematology analyzer.


Outcomes: The extent of serum PCT was considerably completely different between the BS group and the management group (P <0.01) however didn’t present a big distinction between FS group and the management group (P> 0.05); CRP have been statistically important variations between the FS group and the management group (P <0.01) however not statistically important between the BS and the management group (P> 0.05).

Space underneath the receiver working attribute (ROC) curves have been 0.979 and 0.826 for PCT / CRP within the group of BS and FS group, one of the best cutoff worth of 0.93 and 33.27, respectively; the sensitivity and specificity of PCT / CRP in two teams are 0.962 / 0.679 and 0.964 / 0.964, respectively.


Conclusion: In contrast with CRP, PCT is extra delicate in diagnosing BS however will not be delicate for the analysis of FS. Subsequently, PCR is a helpful biomarker to differentiate BS from FS in neonates with late-onset sepsis.

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Description: Mantle Cell Lymphoma Peripheral Blood Mononuclear Cells are density separated by Ficoll-Paque from Mantle Cell Lymphoma peripheral blood. Mantle Cell Lymphoma PBMCs are available in untreated and relapsed/refractory stages.

Human Acute Myeloid Leukemia Peripheral Blood Mononuclear Cells (Newly Diagnosed)
ABC-TC3028 1 vial Ask for price
Description: PBMCs are isolated from Acute Myeloid Leukemia-PB by diluting the blood with phosphate-buffered saline and using gradient separation techniques. After centrifugation, the Mononuclear Cells layer is collected. Acute Myeloid Leukemia Peripheral Blood Mononuclear Cells are available in the newly diagnosed and relapsed/refractory stages.

Human Acute Lymphoid Leukemia Peripheral Blood Mononuclear Cells (Relapsed/Refractory)
ABC-TC3010 1 vial Ask for price
Description: PBMCs are isolated from Acute Lymphoid Leukemia peripheral blood by diluting the whole blood with PBS and using gradient separation techniques. After centrifugation, the mononuclear cell layer is collected. Mononuclear Cells can be processed further to isolate subpopulations. Acute Lymphoid Leukemia Peripheral Blood Mononuclear Cells are available in the newly diagnosed and relapsed/refractory stages.
Diagnostic utility of procalcitonin as a biomarker for late-onset neonatal sepsis
Diagnostic utility of procalcitonin as a biomarker for late-onset neonatal sepsis

Neonatal untimely Intestine colonization with carbapenem-resistant Enterobacteriaceae and Its Affiliation with Neonatal Sepsis and Mrs. Intestine Flora

Background: Multidrug-resistant Gram-negative neonatal sepsis related to excessive mortality and morbidity. Mucosal colonization of those organisms within the hospital can have an effect on neonates to septicemia.


Goal: The purpose of this examine was to find out the prevalence and patterns of preterm neonatal intestinal colonization with carbapenem-resistant Enterobacteriaceae and determine danger elements related to colonization.


The setting and design: The examine was a potential observational examine carried out at Stage three neonatal unit of a tertiary care hospital.


Strategies: Stool samples collected from preterm infants instantly after delivery and at 1 and three weeks of age after approval. maternal stool samples collected inside 48 hours after supply. Predetermined antenatal, neonatal, and environmental danger elements have been recorded. Isolation and identification of the organism is finished in an ordinary manner; The antibiotic susceptibility carried out by Kirby-Bauer methodology and the outcomes interpreted in accordance with medical pointers and Laboratory Requirements Institute.


Outcomes: Seventy-one p.c of the infants have been colonized by Gram-negative micro organism (GNB) at delivery, and is 100% occupied on the finish of 1 week. Generally remoted organisms are Escherichia coli, Klebsiella, NFGNB (Nonfermenting Gram-negative bacilli), Pseudomonas, and Enterobacter. Sixty-eight p.c of infants colonized with extended-spectrum beta-lactamase-producing organisms, and 5% of the infants have been colonized with carbapenem-resistant organisms (CRO). In infants who develop culture-positive sepsis, 21% concordance within the intestines and blood pressure. There is no such thing as a relationship between mom and toddler colonization.

Mammalian Mitochondria Isolation Kit for Cultured Cells
abx098856-100l 100 µl
EUR 912.5

Mammalian Mitochondria Isolation Kit for Cultured Cells
abx098856-1ml 1 ml Ask for price

Mammalian Mitochondria Isolation Kit for Cultured Cells
abx098856-200l 200 µl Ask for price

Mammalian Mitochondria Isolation Kit for Cultured Cells
20-abx098856
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  • 2 rxns
  • 50 rxns

Minute TM Mitochondria Isolation Kit for Muscle Tissues/Cultured Muscle Cells (50 Tests)
MM-038 each
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Minute TM Mitochondria Isolation Kit for Mammalian Cells and Tissues(50 Tests)
MP-007 each
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Mammalian Mitochondria Isolation Kit for Tissue
abx098857-100l 100 µl
EUR 912.5

Mammalian Mitochondria Isolation Kit for Tissue
abx098857-1ml 1 ml Ask for price

Mammalian Mitochondria Isolation Kit for Tissue
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Mammalian Mitochondria Isolation Kit for Tissue
abx098857-50rxns 50 rxns
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Mitochondria Isolation Kit (Mammalian cells / tissues)
P507L - Ask for price

Tissue Mitochondria Isolation Kit
abx090631-100l 100 µl
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Tissue Mitochondria Isolation Kit
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Tissue Mitochondria Isolation Kit
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Tissue Mitochondria Isolation Kit
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EUR 135

Tissue Mitochondria Isolation Kit
MBS355483-50Tests 50Tests
EUR 255

Tissue Mitochondria Isolation Kit
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Tissue Mitochondria Isolation Kit
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Tissue Mitochondria Isolation Kit
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Genomic DNA Isolation Reagent Kit(Blood/Cultured Cell/Tissue)
PDR05-0100 100 rxns
EUR 154

Genomic DNA Isolation Reagent Kit (Blood/Cultured Cell/Tissue) (Reagent Based)
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EUR 300

Genomic DNA Isolation Reagent Kit (Blood/Cultured Cell/Tissue) (Reagent Based)
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Geneaidâ„¢ DNA Isolation Kit (Cultured Cell)
GEC005 each
EUR 3

Geneaidâ„¢ DNA Isolation Kit (Cultured Cell)
GEC1.5K each
EUR 360

Geneaidâ„¢ DNA Isolation Kit (Cultured Cell)
GEC150 each
EUR 60

Geneaidâ„¢ DNA Isolation Kit (Cultured Cell) Plus
GEC1.5K-A each
EUR 400

Total RNA Isolation Kit (Blood/Cultured Cell/Fungus)
PDC04-0100 100 rxns
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Genomic DNA Isolation Kit (Blood/Cultured Cell/Fungus)
PDC09-0100 100 rxns
EUR 99

ExoQuick-TC ULTRA EV Isolation Kit for Tissue Culture Media
EQULTRA-20TC-1 20 reactions
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ExoQuick Exosome Isolation and RNA Purification kit (for Tissue Culture Media)
EQ806TC-1 10 preps
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Cell Mitochondria Isolation Kit
abx090630-100l 100 µl
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Cell Mitochondria Isolation Kit
abx090630-1ml 1 ml Ask for price

Cell Mitochondria Isolation Kit
abx090630-200l 200 µl Ask for price

Cell Mitochondria Isolation Kit
abx090630-50100tests 50-100 tests
EUR 309.6

Cell Mitochondria Isolation Kit
ETF3601 100 assays
EUR 135

Cell Mitochondria Isolation Kit
MBS355486-50Tests 50Tests
EUR 255

Cell Mitochondria Isolation Kit
MBS355486-5x50Tests 5x50Tests
EUR 1130

Cell Mitochondria Isolation Kit
MBS8579523-100Assays 100Assays
EUR 245

Cell Mitochondria Isolation Kit
MBS8579523-5x100Assays 5x100Assays
EUR 1105

Genomic DNA Isolation Kit, Plus (Blood/Cultured Cell/Fungus)
MBS402040-100Reactions 100Reactions
EUR 310

Mitochondria Isolation Kit
AR0156 1 kit
EUR 127.2

Mitochondria Isolation Kit
BC156-50T 50T
EUR 150

Genomic DNA Isolation Kit (Blood/Cultured Cell/Fungus) (Column Based)
MBS402036-100Reactions 100Reactions
EUR 300

Genomic DNA Isolation Kit (Blood/Cultured Cell/Fungus) (Column Based)
MBS402036-4Reactions 4Reactions
EUR 185

Cells and Tissue DNA Isolation Kit
53100 50 Preps
EUR 117

Cells and Tissue DNA Isolation Kit
53140 4 Preps
EUR 12

Yeast Mitochondria Isolation Kit
K259-50 each
EUR 502.8

Cells and Tissue DNA Isolation Kit Dx
Dx53100 50 Preps
EUR 131.4

Mitochondrion Extraction Kit (Cultured Cells)
MBS9718637-200Tests 200Tests
EUR 230

Mitochondrion Extraction Kit (Cultured Cells)
MBS9718637-50Tests 50Tests
EUR 170

Mitochondrion Extraction Kit (Cultured Cells)
MBS9718637-5x200Tests 5x200Tests
EUR 1010

Cells and Tissue DNA Isolation Micro Kit
57300 50 Preps
EUR 125.4

ExKineâ„¢ Mitochondrion Extraction Kit (Cultured Cells)
KTP4003-200T 200 T
EUR 149
Description: Abbkine ExKineâ„¢ Mitochondrion Extraction Kit (Cultured Cells) enables isolation of of intact mitochondria from cultured mammalian cells.

ExKineâ„¢ Mitochondrion Extraction Kit (Cultured Cells)
KTP4003-50T 50 T
EUR 49
Description: Abbkine ExKineâ„¢ Mitochondrion Extraction Kit (Cultured Cells) enables isolation of of intact mitochondria from cultured mammalian cells.

ExKineâ„¢ Mitochondrion Extraction Kit (Cultured Cells)
KTP4003-each each Ask for price

Cells and Tissue DNA Isolation Kit (Magnetic Bead System)
59100 50 Preps
EUR 95.4

Exosome Isolation kit (for cell culture media)
P100 10 rxn
EUR 199

Exosome Isolation kit (for cell culture media)
P100L 40 rxn
EUR 1149

Exosome Isolation kit (for cell culture media)
P100S 2 rxn
EUR 69

nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412807-1x96DeepWellPlate 1x96DeepWellPlate
EUR 390

nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412807-5x96DeepWellPlate 5x96DeepWellPlate
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nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412818-10x96DeepWellPlate 10x96DeepWellPlate
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nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412818-2x96DeepWellPlate 2x96DeepWellPlate
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nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412825-4x96DeepWellPlate 4x96DeepWellPlate
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nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412832-24x96DeepWellPlate 24x96DeepWellPlate
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nexttec Genomic DNA Isolation Kit from Tissue and Cells (columns)
MBS412795-10Columns 10Columns
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nexttec Genomic DNA Isolation Kit from Tissue and Cells (columns)
MBS412795-5x10Columns 5x10Columns
EUR 720

nexttec Genomic DNA Isolation Kit from Tissue and Cells (columns)
MBS412804-50Columns 50Columns
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nexttec Genomic DNA Isolation Kit from Tissue and Cells (columns)
MBS412804-5x50Columns 5x50Columns
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Exosome Isolation kit (for stem cell culture media)
P107 10 rxn
EUR 199

Exosome Isolation kit (for stem cell culture media)
P107S 2 rxn
EUR 69

Cells and Tissue DNA Isolation 96-Well Kit (Magnetic Bead System)
62500 2 Plates
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Mitochondrial DNA Isolation Kit
55R-1361 50 assays
EUR 660
Description: Mitochondrial DNA Isolation Kit for use in the research laboratory

Mitochondrial DNA Isolation Kit
K2117-1 1 kit
EUR 953.6
Description: Tools Kit|DNA Isolation Kit#Kits|Tools Kit#Kits

Mitochondrial DNA Isolation Kit
K2117-50 50 assays
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Mitochondrial DNA Isolation Kit
GWB-AXR186 50 assays Ask for price

Mitochondrial DNA Isolation Kit
K280-50 each
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MinuteTM Single Nucleus Isolation Kit for Tissues/Cells (20 preps)
SN-047 each
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Total Protein Extraction Kit for Animal Cultured Cells/Tissues
MBS9719101-50Tests 50Tests
EUR 250

Total Protein Extraction Kit for Animal Cultured Cells/Tissues
MBS9719101-5Tests 5Tests
EUR 160

Total Protein Extraction Kit for Animal Cultured Cells/Tissues
MBS9719101-5x50Tests 5x50Tests
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Mitochondria-Isolation-Kit-for-Tissue-and-Cultured-Cells
KC010100 1 kit
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Hair Mitochondrial DNA Isolation Kit
69400 50 Preps
EUR 93

EASYspin RNA Isolation Kit (For Tissues & Cells)(Without Phenol & Chloroform)
MBS355950-50Tests 50Tests
EUR 435

EASYspin RNA Isolation Kit (For Tissues & Cells)(Without Phenol & Chloroform)
MBS355950-5x50Tests 5x50Tests
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Cell Culture Media Exosome Purification and RNA Isolation Mini Kit
60700 50 Preps
EUR 611.4

Cell Culture Media Exosome Purification and RNA Isolation Midi Kit
60800 25 Preps
EUR 641.4

Cell Culture Media Exosome Purification and RNA Isolation Maxi Kit
60900 15 Preps
EUR 411

MinuteTM Lipid Raft Isolation Kit for Mammalian Cells/Tissues (20 tests)
LR-039 each
EUR 545

MinuteTM Lipid Raft Isolation Kit for Mammalian Cells/Tissues (20 tests)
LR-042 each
EUR 545


Conclusion: The outcomes confirmed that neonatal intestinal colonized by NAM from delivery onwards. Nonetheless, the low price of colonization by the CRO. An affiliation was additionally noticed between colonization and late-onset sepsis.

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