Diagnostic utility of procalcitonin as a biomarker

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October 2024
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Diagnostic utility of procalcitonin as a biomarker for late-onset neonatal sepsis

Background: To discover the diagnostic utility procalcitonin (PCT) as a biomarker for late-onset neonatal sepsis (Lons).


Strategies: The medical and laboratory knowledge from 131 sufferers within the neonatal neonatal intensive care unit (NICU) of our heart (Division of Neonatology, Renmin Hospital of Wuhan College) on June 1, 2015, to Could 31, 2018, have been retrospectively analyzed.

These sufferers have been divided into three teams primarily based on the situation of their illness: bacterial sepsis (BS) group (n = 47), sepsis mushrooms (FS) group (n = 39), and a gaggle of regular controls (n = 45, with out sepsis). blood tradition, routine blood exams, and testing for PCT protein and C-reactive (CRP) is carried out in all three teams. Each the PCT and CRP have been measured utilizing enzyme-linked immunosorbent assay (ELISA). blood cultures carried out in automated blood tradition system. Routine blood exams finished utilizing absolutely automated hematology analyzer.


Outcomes: The extent of serum PCT was considerably completely different between the BS group and the management group (P <0.01) however didn’t present a big distinction between FS group and the management group (P> 0.05); CRP have been statistically important variations between the FS group and the management group (P <0.01) however not statistically important between the BS and the management group (P> 0.05).

Space underneath the receiver working attribute (ROC) curves have been 0.979 and 0.826 for PCT / CRP within the group of BS and FS group, one of the best cutoff worth of 0.93 and 33.27, respectively; the sensitivity and specificity of PCT / CRP in two teams are 0.962 / 0.679 and 0.964 / 0.964, respectively.


Conclusion: In contrast with CRP, PCT is extra delicate in diagnosing BS however will not be delicate for the analysis of FS. Subsequently, PCR is a helpful biomarker to differentiate BS from FS in neonates with late-onset sepsis.

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Description: Mantle Cell Lymphoma Peripheral Blood Mononuclear Cells are density separated by Ficoll-Paque from Mantle Cell Lymphoma peripheral blood. Mantle Cell Lymphoma PBMCs are available in untreated and relapsed/refractory stages.

Human Acute Myeloid Leukemia Peripheral Blood Mononuclear Cells (Newly Diagnosed)
ABC-TC3028 1 vial Ask for price
Description: PBMCs are isolated from Acute Myeloid Leukemia-PB by diluting the blood with phosphate-buffered saline and using gradient separation techniques. After centrifugation, the Mononuclear Cells layer is collected. Acute Myeloid Leukemia Peripheral Blood Mononuclear Cells are available in the newly diagnosed and relapsed/refractory stages.

Human Multiple Myeloma Peripheral Blood Mononuclear Cells (Newly Diagnosed/Untreated)
ABC-TC3950 1 vial Ask for price
Description: Multiple Myeloma Peripheral Blood Mononuclear Cells are isolated from Multiple Myeloma-peripheral blood by diluting the blood with phosphate-buffered salineand using gradient separation techniques. After centrifugation, the Mononuclear Cells layer is collected. Mononuclear Cells can be processed further to isolate subpopulations. Multiple Myeloma PBMCs products are available in both the newly diagnosed and the relapsed/refractory stages.
Diagnostic utility of procalcitonin as a biomarker for late-onset neonatal sepsis
Diagnostic utility of procalcitonin as a biomarker for late-onset neonatal sepsis

Neonatal untimely Intestine colonization with carbapenem-resistant Enterobacteriaceae and Its Affiliation with Neonatal Sepsis and Mrs. Intestine Flora

Background: Multidrug-resistant Gram-negative neonatal sepsis related to excessive mortality and morbidity. Mucosal colonization of those organisms within the hospital can have an effect on neonates to septicemia.


Goal: The purpose of this examine was to find out the prevalence and patterns of preterm neonatal intestinal colonization with carbapenem-resistant Enterobacteriaceae and determine danger elements related to colonization.


The setting and design: The examine was a potential observational examine carried out at Stage three neonatal unit of a tertiary care hospital.


Strategies: Stool samples collected from preterm infants instantly after delivery and at 1 and three weeks of age after approval. maternal stool samples collected inside 48 hours after supply. Predetermined antenatal, neonatal, and environmental danger elements have been recorded. Isolation and identification of the organism is finished in an ordinary manner; The antibiotic susceptibility carried out by Kirby-Bauer methodology and the outcomes interpreted in accordance with medical pointers and Laboratory Requirements Institute.


Outcomes: Seventy-one p.c of the infants have been colonized by Gram-negative micro organism (GNB) at delivery, and is 100% occupied on the finish of 1 week. Generally remoted organisms are Escherichia coli, Klebsiella, NFGNB (Nonfermenting Gram-negative bacilli), Pseudomonas, and Enterobacter. Sixty-eight p.c of infants colonized with extended-spectrum beta-lactamase-producing organisms, and 5% of the infants have been colonized with carbapenem-resistant organisms (CRO). In infants who develop culture-positive sepsis, 21% concordance within the intestines and blood pressure. There is no such thing as a relationship between mom and toddler colonization.

Mammalian Mitochondria Isolation Kit for Cultured Cells
abx098856-1ml 1 ml Ask for price

Mammalian Mitochondria Isolation Kit for Cultured Cells
abx098856-200l 200 µl Ask for price

Mitochondria Isolation Kit (Cultured Cells)
K1138-10 10rxns
EUR 28
Description: Mitochondria Isolation Kit

Mitochondria Isolation Kit (Cultured Cells)
K1138-20 20rxns
EUR 44
Description: Mitochondria Isolation Kit

Mitochondria Isolation Kit (Cultured Cells)
K1138-30 30rxns
EUR 56
Description: Mitochondria Isolation Kit

Minute TM Mitochondria Isolation Kit for Muscle Tissues/Cultured Muscle Cells (50 Tests)
MM-038 each
EUR 535

Minute TM Mitochondria Isolation Kit for Mammalian Cells and Tissues(50 Tests)
MP-007 each
EUR 535

Mammalian Mitochondria Isolation Kit for Tissue
abx098857-50rxns 50 rxns
EUR 493.2

Mammalian Mitochondria Isolation Kit for Tissue
abx098857-100l 100 µl
EUR 912.5

Mammalian Mitochondria Isolation Kit for Tissue
abx098857-1ml 1 ml Ask for price

Mammalian Mitochondria Isolation Kit for Tissue
abx098857-200l 200 µl Ask for price

Mitochondria Isolation Kit (Mammalian cells / tissues)
P507L - Ask for price

Tissue Mitochondria Isolation Kit
abx090631-50100assays 50-100 assays
EUR 309.6

Tissue Mitochondria Isolation Kit
ETF3606 100 assays
EUR 135

Tissue Mitochondria Isolation Kit
abx090631-100l 100 µl
EUR 187.5

Tissue Mitochondria Isolation Kit
abx090631-1ml 1 ml Ask for price

Tissue Mitochondria Isolation Kit
abx090631-200l 200 µl Ask for price

Tissue Mitochondria Isolation Kit
MBS8579524-100Assays 100Assays
EUR 245

Tissue Mitochondria Isolation Kit
MBS8579524-5x100Assays 5x100Assays
EUR 1105

Tissue Mitochondria Isolation Kit
MBS355483-50Tests 50Tests
EUR 255

Tissue Mitochondria Isolation Kit
MBS355483-5x50Tests 5x50Tests
EUR 1130

Genomic DNA Isolation Reagent Kit(Blood/Cultured Cell/Tissue)
PDR05-0100 100 rxns
EUR 154

Genomic DNA Isolation Reagent Kit (Blood/Cultured Cell/Tissue) (Reagent Based)
MBS402054-100Reactions 100Reactions
EUR 300

Genomic DNA Isolation Reagent Kit (Blood/Cultured Cell/Tissue) (Reagent Based)
MBS402054-4Reactions 4Reactions
EUR 185

Geneaid™ DNA Isolation Kit (Cultured Cell)
GEC005 each
EUR 3

Geneaid™ DNA Isolation Kit (Cultured Cell)
GEC1.5K each
EUR 360

Geneaid™ DNA Isolation Kit (Cultured Cell)
GEC150 each
EUR 60

Geneaid™ DNA Isolation Kit (Cultured Cell) Plus
GEC1.5K-A each
EUR 400

Total RNA Isolation Kit (Blood/Cultured Cell/Fungus)
PDC04-0100 100 rxns
EUR 220

Genomic DNA Isolation Kit (Blood/Cultured Cell/Fungus)
PDC09-0100 100 rxns
EUR 99

ExoQuick-TC ULTRA EV Isolation Kit for Tissue Culture Media
EQULTRA-20TC-1 20 reactions
EUR 518

ExoQuick Exosome Isolation and RNA Purification kit (for Tissue Culture Media)
EQ806TC-1 10 preps
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Cell Mitochondria Isolation Kit
abx090630-50100tests 50-100 tests
EUR 309.6

Cell Mitochondria Isolation Kit
ETF3601 100 assays
EUR 135

Cell Mitochondria Isolation Kit
abx090630-100l 100 µl
EUR 187.5

Cell Mitochondria Isolation Kit
abx090630-1ml 1 ml Ask for price

Cell Mitochondria Isolation Kit
abx090630-200l 200 µl Ask for price

Cell Mitochondria Isolation Kit
MBS8579523-100Assays 100Assays
EUR 245

Cell Mitochondria Isolation Kit
MBS8579523-5x100Assays 5x100Assays
EUR 1105

Cell Mitochondria Isolation Kit
MBS355486-50Tests 50Tests
EUR 255

Cell Mitochondria Isolation Kit
MBS355486-5x50Tests 5x50Tests
EUR 1130

Genomic DNA Isolation Kit, Plus (Blood/Cultured Cell/Fungus)
MBS402040-100Reactions 100Reactions
EUR 310

Mitochondria Isolation Kit
AR0156 1 kit
EUR 127.2

Mitochondria Isolation Kit
BC156-50T 50T
EUR 150

Genomic DNA Isolation Kit (Blood/Cultured Cell/Fungus) (Column Based)
MBS402036-100Reactions 100Reactions
EUR 300

Genomic DNA Isolation Kit (Blood/Cultured Cell/Fungus) (Column Based)
MBS402036-4Reactions 4Reactions
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Yeast Mitochondria Isolation Kit
K259-50 each
EUR 502.8

Mitochondrion Extraction Kit (Cultured Cells)
MBS9718637-200Tests 200Tests
EUR 230

Mitochondrion Extraction Kit (Cultured Cells)
MBS9718637-50Tests 50Tests
EUR 170

Mitochondrion Extraction Kit (Cultured Cells)
MBS9718637-5x200Tests 5x200Tests
EUR 1010

ExKine™ Mitochondrion Extraction Kit (Cultured Cells)
KTP4003-each each Ask for price

ExKine™ Mitochondrion Extraction Kit (Cultured Cells)
KTP4003-200T 200 T
EUR 149
Description: Abbkine ExKine™ Mitochondrion Extraction Kit (Cultured Cells) enables isolation of of intact mitochondria from cultured mammalian cells.

ExKine™ Mitochondrion Extraction Kit (Cultured Cells)
KTP4003-50T 50 T
EUR 49
Description: Abbkine ExKine™ Mitochondrion Extraction Kit (Cultured Cells) enables isolation of of intact mitochondria from cultured mammalian cells.

Exosome Isolation kit (for cell culture media)
P100 10 rxn
EUR 199

Exosome Isolation kit (for cell culture media)
P100L 40 rxn
EUR 769

Exosome Isolation kit (for cell culture media)
P100S 2 rxn
EUR 69

nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412807-1x96DeepWellPlate 1x96DeepWellPlate
EUR 390

nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412807-5x96DeepWellPlate 5x96DeepWellPlate
EUR 1765

nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412818-10x96DeepWellPlate 10x96DeepWellPlate
EUR 3095

nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412818-2x96DeepWellPlate 2x96DeepWellPlate
EUR 675

nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412825-4x96DeepWellPlate 4x96DeepWellPlate
EUR 1230

nexttec Genomic DNA Isolation Kit from Tissue and Cells (plates)
MBS412832-24x96DeepWellPlate 24x96DeepWellPlate
EUR 6690

nexttec Genomic DNA Isolation Kit from Tissue and Cells (columns)
MBS412795-10Columns 10Columns
EUR 160

nexttec Genomic DNA Isolation Kit from Tissue and Cells (columns)
MBS412795-5x10Columns 5x10Columns
EUR 720

nexttec Genomic DNA Isolation Kit from Tissue and Cells (columns)
MBS412804-50Columns 50Columns
EUR 295

nexttec Genomic DNA Isolation Kit from Tissue and Cells (columns)
MBS412804-5x50Columns 5x50Columns
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Exosome Isolation kit (for stem cell culture media)
P107 10 rxn
EUR 199

Exosome Isolation kit (for stem cell culture media)
P107S 2 rxn
EUR 69

Mitochondrial DNA Isolation Kit
55R-1361 50 assays
EUR 660
Description: Mitochondrial DNA Isolation Kit for use in the research laboratory

Mitochondrial DNA Isolation Kit
K2117-1 1 kit
EUR 686
Description: Isolates mt. DNA, no genomic DNA contamination

Mitochondrial DNA Isolation Kit
K2117-50 50 assays
EUR 718.8

Mitochondrial DNA Isolation Kit
GWB-AXR186 50 assays Ask for price

Mitochondrial DNA Isolation Kit
K280-50 each
EUR 705.6

MinuteTM Single Nucleus Isolation Kit for Tissues/Cells (20 preps)
SN-047 each
EUR 435

Total Protein Extraction Kit for Animal Cultured Cells/Tissues
MBS9719101-50Tests 50Tests
EUR 250

Total Protein Extraction Kit for Animal Cultured Cells/Tissues
MBS9719101-5Tests 5Tests
EUR 160

Total Protein Extraction Kit for Animal Cultured Cells/Tissues
MBS9719101-5x50Tests 5x50Tests
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EASYspin RNA Isolation Kit (For Tissues & Cells)(Without Phenol & Chloroform)
MBS355950-50Tests 50Tests
EUR 435

EASYspin RNA Isolation Kit (For Tissues & Cells)(Without Phenol & Chloroform)
MBS355950-5x50Tests 5x50Tests
EUR 1935

MinuteTM Lipid Raft Isolation Kit for Mammalian Cells/Tissues (20 tests)
LR-039 each
EUR 545

MinuteTM Lipid Raft Isolation Kit for Mammalian Cells/Tissues (20 tests)
LR-042 each
EUR 545

MinuteTM Single Nucleus Isolation Kit for Neuronal Tissues/Cells (20 preps)
BN-020 each
EUR 435

ExoQualiTM Human Exosome Capture and Isolation Kits (for Cell Culture Media/ Urine) (CD9 Capture Beads)
CEIK-097L-10T 10T Ask for price

ExoQualiTM Human Exosome Capture and Isolation Kits (for Cell Culture Media/ Urine) (CD63 Capture Beads)
CEIK-098L-10T 10T Ask for price

ExoQualiTM Human Exosome Capture and Isolation Kits (for Cell Culture Media/ Urine) (CD81 Capture Beads)
CEIK-099L-10T 10T Ask for price

ExoQualiTM Mouse Exosome Capture and Isolation Kits (for Cell Culture Media/ Urine) (mCD9 Capture Beads)
CEIK-104L-10T 10T Ask for price

ExoQualiTM Mouse Exosome Capture and Isolation Kits (for Cell Culture Media/ Urine) (mCD63 Capture Beads)
CEIK-105L-10T 10T Ask for price

Mitochondrial DNA Isolation Kit, Catalog: PI-0105
PI-0105 50 isolations
EUR 465
Description: To isolate intact mitochondrial DNA from a variety of cells and tissue types without contamination from genomic DNA. 

ExoQualiTM Mouse Exosome Capture and Isolation Kits (for Cell Culture Media/ Urine) (mCD9/CD63 Capture Beads)
CEIK-106L-10T 10T Ask for price

ExoQualiTM Human Exosome Capture and Isolation Kits (for Cell Culture Media/ Urine) (CD9/CD63/CD81 Capture Beads)
CEIK-100L-10T 10T Ask for price

ExKine™ Pro Total Protein Extraction Kit for Animal Cultured Cells/Tissues
KTP3007-each each Ask for price


Conclusion: The outcomes confirmed that neonatal intestinal colonized by NAM from delivery onwards. Nonetheless, the low price of colonization by the CRO. An affiliation was additionally noticed between colonization and late-onset sepsis.

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