Neonatal sepsis at Mulago

September 2023
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Background: Sepsis is the third most typical explanation for dying amongst neonates, with about 225,000 newborns die every year globally. Information on the microbial etiology of neonatal sepsis and antimicrobial resistance profile of causative brokers are required to tell the focused and efficient remedy and prevention methods.


Goal: To find out the proportion of newborns with signs and indicators of sepsis have optimistic blood tradition, bacterial etiology, the antimicrobial resistance patterns and elements related to culture-optimistic and deaths at Mulago nationwide referral hospital in Uganda.


Strategies:
We performed a cross-sectional examine amongst 359 neonates with signs and indicators of sepsis have been introduced to the pediatric emergency care unit of Mulago nationwide referral hospital from mid-January to the top of December 2018. We did a blood tradition and antimicrobial susceptibility assessments, and do polymerase chain response to determine methicillin-resistant Staphylococcus aureus (MRSA) isolates. We used multivariable logistic regression to estimate the connection between potential threat elements and culture-positive neonatal sepsis.


Findings: Of 359 neonates have been recruited, 46 (12.8%; 95% CI 9.5%, 16.7%) had optimistic blood cultures. The dominant micro organism remoted have been Staphylococcus aureus in 29 (63.0%), Escherichia coli in seven (15.2%), and Klebsiella pneumoniae in 5 (10.9%). Of the 46 pathogens, 73.9% have been proof against ampicillin, gentamicin and 23.9% to eight.7% for ceftriaxone. We remoted MRSA from blood specimens of 19 (5.3%) of 359 neonates, whereas 3 (0.8%) grew prolonged spectrum beta-lactamase producers. The case of threat of dying amongst neonates with neonatal sepsis is 9.5% (95% CI: 6.6%, 13.0%). cesarean part was strongly related to culture-positive sepsis (adjusted odds ratio 3.45, 95% CI: 1.2, 10.1).


Conclusion: Considered one of eight neonates with medical indicators of sepsis-causing pathogens micro organism rising chance. S. aureus is a serious pathogen remoted and one-third of the MRSA isolates. A major proportion of the remoted pathogenic micro organism proof against first and second line antibiotics used for the remedy of neonatal sepsis. There’s a must evaluation the present remedy tips for neonatal sepsis.

Positively Selected Normal Peripheral Blood CD19+ B Cells, Cryopreserved

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Normal Human Peripheral Blood Mononuclear Cells, Frozen

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 Neonatal sepsis at Mulago national referral hospital in Uganda: Etiology, antimicrobial resistance, associated factors and case fatality risk
Neonatal sepsis at Mulago nationwide referral hospital in Uganda: Etiology, antimicrobial resistance, related elements and case fatality threat

Micro-erythrocyte sedimentation price in Neonatal Sepsis of Tertiary Hospital: A Descriptive Examine of Cross-sectional

Introduction: Neonatal sepsis is a very powerful explanation for morbidity and mortality amongst low delivery weight and untimely infants in growing international locations. The principle goal of this examine was to seek out the extent of micro-erythrocyte sedimentation price in neonatal sepsis.


Strategies:
This examine is a descriptive cross-sectional examine performed on the neonatal unit over a six month interval (November 2019-April 2020). All untimely infants, time period and post-term with neonatal sepsisdelivered at Kathmandu Medical Faculty Instructing Hospital have been enrolled. moral permission is acquired from the Institutional Overview Committee of Kathmandu Medical Faculty (Ref: 181 020 191). The sampling technique utilized comfy and statistical evaluation carried out with the statistical bundle for social sciences model 19.


Outcomes: Of the 75 infants, affirm sepsis was 13 (17.3%), the potential of sepsis was 40 (53.4%) and suspected sepsis was 22 (29.2%). micro-level elevated erythrocyte sedimentation (≥15mm at hr 1) in 25 (33.3%) infants with a imply micro-erythrocyte sedimentation price of 9.32 ± 5.4 (2-18) mm hr 1. micro degree elevated erythrocyte sedimentation seen in relation to the kind of sepsis and C-reactive protein.

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79059-1 30 million cells
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Normal Human Peripheral Blood Mononuclear Cells, Frozen -100 million cells

79059-2 100 million cells
EUR 580
Description: Cryopreserved vial (30 x 10^6 cells) of freshly isolated primary human peripheral blood mononuclear cells (PBMCs) from a healthy donor, isolated from leukapheresis / apheresis samples using Ficoll gradient. After isolation, the PBMCs were stained to identify sub populations and evaluated for viability by flow cytometry. Cells were cryopreserved in serum-free Cryostor CS10 at a controlled rate.

Human Peripheral Blood Mononuclear Cell Isolation and Viability Kit

K541-30 each
EUR 451.2

AnaPrep Blood DNA Extraction Kit 1200 (48) For extracting genomic DNA from mammalian whole blood, peripheral mononuclear cell, or buffy coat. Sample volume range: up to 1 ml

Z1322002 1 kit (48 extractions) Including all required plastic disposables
EUR 419

AnaPrep Blood DNA Extraction Kit 200 (48) For extracting genomic DNA from mammalian whole blood, peripheral mononuclear cell, or buffy coat. Sample volume range: up to 400 µl

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Description: Human peripheral blood leukocyte tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human peripheral blood leukocyte tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated peripheral blood leukocyte tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated peripheral blood leukocyte tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

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Total RNA - Human Adult Normal Tissue: Peripheral Blood Leukocyte

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Membrane Protein - Human Adult Normal Tissue: Peripheral Blood Leukocyte

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Rat Anti Rat Rt6.1 (Peripheral T Cells) Monoclonal Antibody

CABT-49825RR 2 ml
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96 Well Human Adult Normal Genomic DNA Plate - Peripheral Blood Leukocyte

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Methylated & Low-Methylated DNA Matched Pair - Human Peripheral Blood Leukocyte

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Genomic DNA - Human Adult Normal Tissue: Peripheral Blood Leukocyte, from a single donor

D1234148 100 ug
EUR 286

HL-60 Cell Slide (Human (36yrs, Female) peripheral blood promyeloblast, acute promyelocytic leukemia) (5 slides/pk)

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Total RNA - Human Adult Normal Tissue: Peripheral Blood Leukocyte, from 4 different donors, 2 male and 2 female. 1 ug/ul concentration

R1234148-10-P04 10x10 µg
EUR 2199

Peripheral nerve tumor tissue array

SO1001a each
EUR 306
Description: Peripheral nerve tumor tissue array, including TNM and clinical stage, 50 cases/100 cores, replaced by SO1001b

Peripheral nerve tumor tissue array

SO1001b each
EUR 306
Description: Peripheral nerve tumor tissue array, including TNM and clinical stage, 50 cases/100 cores, replacing SO1001a

Rat Peripheral myelin protein 22 (Pmp22)

1-CSB-CF018241RA
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Description: Recombinant Rat Peripheral myelin protein 22(Pmp22) expressed in in vitro E.coli expression system

Peripheral Myelin Protein 22 (PMP22) Monoclonal Antibody (Human)

4-MAC746Hu21
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  • EUR 386.40
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Description: A Mouse monoclonal antibody against Human Peripheral Myelin Protein 22 (PMP22)

Peripheral Myelin Protein 22 (PMP22) Blocking Peptide

20-abx061188
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  • EUR 943.20
  • EUR 463.20
  • EUR 238.80
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Description: A Mouse monoclonal antibody against Human Peripheral Myelin Protein 22 (PMP22). This antibody is labeled with PE.

Peripheral Myelin Protein 2 (PMP2) Antibody

20-abx114394
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  • EUR 477.60
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Peripheral Myelin Protein 22 (PMP22) Monoclonal Antibody (Human), APC

4-MAC746Hu21-APC
  • EUR 429.60
  • EUR 4146.00
  • EUR 1148.40
  • EUR 549.60
  • EUR 268.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Mouse monoclonal antibody against Human Peripheral Myelin Protein 22 (PMP22). This antibody is labeled with APC.

Peripheral Myelin Protein 22 (PMP22) Monoclonal Antibody (Human), Cy3

4-MAC746Hu21-Cy3
  • EUR 522.00
  • EUR 5478.00
  • EUR 1482.00
  • EUR 682.80
  • EUR 309.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Peripheral Myelin Protein 22 (PMP22). This antibody is labeled with Cy3.

Peripheral Myelin Protein 22 (PMP22) Monoclonal Antibody (Human), HRP

4-MAC746Hu21-HRP
  • EUR 392.40
  • EUR 3613.20
  • EUR 1015.20
  • EUR 495.60
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Peripheral Myelin Protein 22 (PMP22). This antibody is labeled with HRP.

Peripheral Myelin Protein 22 (PMP22) Antibody

20-abx217831
  • EUR 510.00
  • EUR 410.40
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Peripheral Myelin Protein 22 (PMP22) Antibody

20-abx103057
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
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  • 1 mg
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Peripheral Myelin Protein 22 (PMP22) Antibody

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Peripheral Myelin Protein 22 (PMP22) Antibody

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  • 1 mg
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Peripheral Myelin Protein 22 (PMP22) Antibody

20-abx177955
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

Peripheral Myelin Protein 22 (PMP22) Antibody

20-abx177956
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Peripheral Myelin Protein 22 (PMP22) Antibody

20-abx133606
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Peripheral Myelin Protein 22 (PMP22) Antibody

abx028584-400ul 400 ul
EUR 627.6

Peripheral Myelin Protein 22 (PMP22) Antibody

abx028584-80l 80 µl
EUR 343.2

Peripheral Myelin Protein 22 (PMP22) Antibody

20-abx131854
  • EUR 410.40
  • EUR 1028.40
  • EUR 526.80
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Peripheral Myelin Protein 22 (PMP22) Antibody

20-abx328779
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Peripheral Myelin Protein 22 (PMP22) Antibody

20-abx304860
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Peripheral Myelin Protein 22 (PMP22) Monoclonal Antibody (Human), FITC

4-MAC746Hu21-FITC
  • EUR 367.20
  • EUR 3340.80
  • EUR 943.20
  • EUR 463.20
  • EUR 238.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Peripheral Myelin Protein 22 (PMP22). This antibody is labeled with FITC.

Recombinant rat Peripheral myelin protein 22

P1725 100ug Ask for price
Description: Recombinant protein for rat Peripheral myelin protein 22

Recombinant mouse Peripheral myelin protein 22

P1724 100ug Ask for price
Description: Recombinant protein for mouse Peripheral myelin protein 22

Recombinant Peripheral Myelin Protein 22 (PMP22)

4-RPC746Hu01
  • EUR 539.33
  • EUR 267.60
  • EUR 1692.48
  • EUR 644.16
  • EUR 1168.32
  • EUR 436.80
  • EUR 4051.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Peripheral Myelin Protein 22 expressed in: E.coli

Rat Peripheral Myelin Protein 22 (PMP22) Protein

20-abx654683
  • EUR 777.60
  • EUR 326.40
  • EUR 2331.60
  • EUR 910.80
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

ELISA kit for Rat Peripheral myelin protein 22

EK3088 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat Peripheral myelin protein 22 in samples from serum, plasma, tissue homogenates and other biological fluids.

Peripheral Myelin Protein 22 (PMP22) Monoclonal Antibody (Human), APC-Cy7

4-MAC746Hu21-APC-Cy7
  • EUR 715.20
  • EUR 8148.00
  • EUR 2154.00
  • EUR 955.20
  • EUR 394.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Peripheral Myelin Protein 22 (PMP22). This antibody is labeled with APC-Cy7.

Recombinant Human Peripheral Myelin Protein-2

7-05908 5µg Ask for price

Recombinant Human Peripheral Myelin Protein-2

7-05909 25µg Ask for price

Recombinant Human Peripheral Myelin Protein-2

7-05910 1mg Ask for price

Neuroblastoma and peripheral nerve tissue array

NB642c each
EUR 306
Description: Neuroblastoma and peripheral nerve tissue array, with INSS stage, IHC marker (CD56/CgA) info, 32 cases/64 cores (core size 1.5mm), replacing NB642b

Peripheral Myelin Protein 22 (PMP22) Antibody (HRP)

20-abx304861
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rat Peripheral Myelin Protein 22 (PMP22) CLIA Kit

20-abx493872
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Peripheral Myelin Protein 22 (PMP22) Protein

20-abx068468
  • EUR 760.80
  • EUR 326.40
  • EUR 2281.20
  • EUR 895.20
  • EUR 543.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Peripheral Myelin Protein 22 (PMP22) Protein

20-abx654682
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Peripheral Myelin Protein 22 (PMP22) Protein

20-abx654684
  • EUR 794.40
  • EUR 326.40
  • EUR 2448.00
  • EUR 944.40
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Peripheral Myelin Protein 22 (PMP22) Antibody (FITC)

20-abx304862
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rat Peripheral myelin protein 22 (PMP22) ELISA Kit

abx256464-96tests 96 tests
EUR 895.2

Rat Peripheral Myelin Protein 22 (PMP22) ELISA Kit

20-abx155988
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Peripheral myelin protein 22 (PMP22) ELISA Kit

abx571185-96tests 96 tests
EUR 886.8

Cow Peripheral myelin protein 22 (PMP22) ELISA Kit

abx516097-96tests 96 tests
EUR 1093.2

Rat Peripheral Myelin Protein 22 (PMP22) ELISA Kit

DLR-PMP22-Ra-48T 48T
EUR 658.8
Description: A sandwich quantitative ELISA assay kit for detection of Rat Peripheral Myelin Protein 22 (PMP22) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Peripheral Myelin Protein 22 (PMP22) ELISA Kit

DLR-PMP22-Ra-96T 96T
EUR 861.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Peripheral Myelin Protein 22 (PMP22) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Pmp22(Peripheral myelin protein 22) ELISA Kit

ER0487 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.094 ng/ml

Rat Pmp22/ Peripheral myelin protein 22 ELISA Kit

E0773Ra 1 Kit
EUR 775.2

ELISA kit for Human Peripheral myelin protein 22

EK3089 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Peripheral myelin protein 22 in samples from serum, plasma, tissue homogenates and other biological fluids.

Rat Peripheral Myelin Protein 22 (PMP22) ELISA Kit

SEC746Ra-10x96wellstestplate 10x96-wells test plate
EUR 6149.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Peripheral Myelin Protein 22 (PMP22) in tissue homogenates, cell lysates and other biological fluids.

Rat Peripheral Myelin Protein 22 (PMP22) ELISA Kit

SEC746Ra-1x48wellstestplate 1x48-wells test plate
EUR 611.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Peripheral Myelin Protein 22 (PMP22) in tissue homogenates, cell lysates and other biological fluids.

Rat Peripheral Myelin Protein 22 (PMP22) ELISA Kit

SEC746Ra-1x96wellstestplate 1x96-wells test plate
EUR 822.24
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Peripheral Myelin Protein 22 (PMP22) in tissue homogenates, cell lysates and other biological fluids.

Rat Peripheral Myelin Protein 22 (PMP22) ELISA Kit

SEC746Ra-5x96wellstestplate 5x96-wells test plate
EUR 3340.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Peripheral Myelin Protein 22 (PMP22) in tissue homogenates, cell lysates and other biological fluids.

Rat Peripheral Myelin Protein 22 (PMP22) ELISA Kit

4-SEC746Ra
  • EUR 6210.00
  • EUR 3280.80
  • EUR 823.20
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Peripheral Myelin Protein 22 (PMP22) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Peripheral Myelin Protein 22 (PMP22) ELISA Kit

RD-PMP22-Ra-48Tests 48 Tests
EUR 668.4

Rat Peripheral Myelin Protein 22 (PMP22) ELISA Kit

RD-PMP22-Ra-96Tests 96 Tests
EUR 930


Conclusion: The bedside micro erythrocyte sedimentation price aids within the analysis of neonatal sepsis.