Prophylactic therapy with human amniotic

September 2023
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Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophages

Prophylactic treatment with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis by the use of immunomodulation by the use of aggregates with peritoneal macrophages

 

Background: No matter newest advances in neonatal care, sepsis stays a critical rationalization for lack of life in neonates. Mesenchymal stem cells derived from quite a few tissues, just like bone marrow, umbilical twine and adipose tissues, has helpful outcomes on grownup sepsis. Although human  a amniotic fluid stem cells (hAFSCs) have properties of mesenchymal stem cells, the efficacy hAFSCs on neonatal sepsis stays to be outlined. This look at objectives to research the therapeutic potential of hAFSCs on neonatal sepsis using a rat model of lipopolysaccharide (LPS) induced sepsis.


Methods: hAFSCs isolated as CD117-positive cells from human amniotic fluid. pet rat three-day-old have been intraperitoneally dealt with with LPS to mimic neonatal sepsis. hAFSCs given each Three hours sooner than or at 0, 3, or 24 hours after publicity to LPS. Serum ranges of inflammatory cytokines, gene expression profiles of the spleen and a lot of organ hurt have been analyzed. hAFSC determined in vivo localization. In vitro LPS stimulation verify is carried out using neonatal rat peritoneal macrophages co-cultured with hAFSCs in cells by contact-dependent / neutral. Immunoregulation throughout the spleen was determined by the usage of DNA microarray analysis.


Outcomes: Prophylactic treatment with hAFSCs improve survival in LPS-treated mice whereas hAFSCs transplant after LPS publicity did not get a response to treatment. Subsequently, pretreatment hAFSC used for all subsequent analysis. elevated ranges of inflammatory cytokines after LPS injection, which was attenuated by pretreatment hAFSC. Furthermore, hurt induced irritation throughout the thoughts, lungs, and liver have been repaired.

hAFSCs collected by peritoneal macrophages and / or transiently accumulates throughout the liver, mesentery, and peritoneum. paracrine parts launched by hAFSCs M1-M2 macrophages induced polarization in cells with contact-independent technique. direct contact between hAFSCs and peritoneal macrophages extra enhanced polarization. spleen microarray analysis confirmed that pretreatment hAFSC cut back the expression of genes involved in apoptosis and irritation after which pressed pulses like receptor 4 signaling pathway.


Conclusions: Prophylactic treatment with hAFSCs improve survival in mice LPS-induced neonatal sepsis. This impression may be mediated by the phenotype change from M1 to M2 in peritoneal macrophages, triggered by hAFSCs in cells by contact-dependent / neutral and subsequent immunomodulation spleen.

 Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophages
Prophylactic treatment with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis by the use of immunomodulation by the use of aggregates with peritoneal macrophages

Endeavor sepsis: sepsis biomarker protocol for locating out neonatal and toddler immune response in malaria-endemic areas

Introduction: Neonatal sepsis outreach all-cause neonatal mortality worldwide and stays a critical burden on the group is low and middle earnings nations. Together with restricted property, endemic morbidity, just like malaria and prematurity, neonatal and toddler predispose to invasive an an infection by altering the neonatal immune response in opposition to the pathogen.

However, good epidemiology, diagnostic and immunological evaluation of neonatal sepsis and impression of being pregnant malaria was on no account completed.


Methods and Analysis: A multicenter potential longitudinal follow-up of 580 infants from starting to a few months in metropolis and suburban Benin will do. At provide, and every week, all kids shall be clinically examined and evaluated for the incidence of sepsis.

Rat Pan B Cells antibody

10R-B124a 50 ug
EUR 910.8
Description: Mouse monoclonal Rat Pan B Cells antibody

Human Peripheral Blood CD3+ T Cells, Fresh

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T-Pro Stacking Buffer

JB03-C002 500ml/BT
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T-Pro MycoClean spray

JT90-R002 500ml/BT
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Human Peripheral Blood CD3+ T Cells, Cryopreserved

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Human Peripheral Blood CD3+ T Cells, Cryopreserved

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T-Pro EZ Gel Solution 8%

JB02-B008M 500ml/BT
EUR 266.4

T-Pro EZ Gel Solution 8%

JB02-B008S 100ml/BT
EUR 162

T-Pro EZ Gel Solution 10%

JB02-B010M 500ml/BT
EUR 266.4

T-Pro EZ Gel Solution 10%

JB02-B010S 100ml/BT
EUR 162

T-Pro EZ Gel Solution 12%

JB02-B012M 500ml/BT
EUR 266.4

T-Pro EZ Gel Solution 12%

JB02-B012S 100ml/BT
EUR 162

T-Pro EZ Gel Solution 15%

JB02-B015M 500ml/BT
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T-Pro EZ Gel Solution 15%

JB02-B015S 100ml/BT
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T-Pro Separating or Resolving Buffer

JB03-C001 500ml/BT
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T-Pro BCA Protein Assay kit

JB04-D001 500assay/KIT
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T-Pro Transfer Blotting buffer (10X)

JB08-H001 500ml/BT
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T-Pro Western Blot Stripping Reagent

JB11-K002 500ml/BT
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JT90-R001M 500ml/BT
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T-Pro Aqua EZ Clean (S)

JT90-R001S 100ml/BT
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JT90-R005M 500ml/BT
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T-Pro EZ stain Gel solution

JT90-R005S 100ml/BT
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T-Pro P-Fect Transfection Reagent

JT97-N005M 1.0ml/vial
EUR 266.4

T-Pro Plasmid Mini Kit (100)

RB94-YPD100 100preps/Kit
EUR 193.2

T-Pro Plasmid Mini Kit (250)

RB94-YPD250 250preps/Kit
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T-Pro Plasmid Midi Kit (20)

RB94-YPI020 20preps/Kit
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T-Pro Plasmid Maxi Kit (10)

RB94-YPM010 10preps/Kit
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T-Pro BCA Protein Assay Reagent A

JB04-D001A 500ml/BT
EUR 204

T-Pro BCA Protein Assay Reagent B

JB04-D001B 12ml/BT
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T-Pro Bradford Protein Assay kit(1X)

JB04-D002 500ml/BT
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T-Pro Fast Blocking Buffer (in PBS)

JK92-W001 500ml/BT
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T-Pro Fast Blocking Buffer (in TBS)

JK92-W002 500ml/BT
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T-Pro Genomic DNA Midi Kit (20)

RB94-NGM020 20preps/kit
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T-Pro Genomic DNA Mini Kit (100)

RB94-NGS100 100preps/kit
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T-Pro Laemmli (SDS sample) Reagent (reducing 4X)

JB06-F002 10ml/BT
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T-Pro Tris-Glycine-SDS running buffer (10X)

JB07-G001 500ml/BT
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T-Pro Tris-Glycine-Native running buffer (10X)

JB07-G002 500ml/BT
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T-Pro Semi Dry Transfer Blotting buffer (10X)

JB08-H002 500ml/BT
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T-Pro Protein Free Blocking Buffer (in PBS)

JK92-W003 500ml/BT
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T-Pro Protein Free Blocking Buffer (in TBS)

JK92-W004 500ml/BT
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T-Pro Nonliposomal Transfection Reagent I (NTR I)

JT97-N001M 1.0ml/vial
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T-Pro Nonliposomal Transfection Reagent II (NTR II)

JT97-N002M 1.0ml/vial
EUR 244.8

T-Pro Nonliposomal Transfection Reagent III (NTR III)

JT97-N006M 1.0ml/vial
EUR 266.4

T-Pro Endotoxin Removal Plasmid Midi kit (25)

RB94-EPI020 20preps/Kit
EUR 297.6

T-Pro Endotoxin Removal Plasmid Maxi kit (10)

RB94-EPM010 10preps/Kit
EUR 318

T-Pro Plant Genomic DNA Midi Kit (20)

RB94-PGM020 20preps/kit
EUR 266.4

T-Pro Plant Genomic DNA Mini Kit (100)

RB94-PGS100 100preps/kit
EUR 266.4

T-Pro Laemmli (SDS sample) Reagent (non-reducing 4X)

JB06-F003 10ml/BT
EUR 151.2

T-Pro LumiFast Plus Chemiluminescence Detection Kit (ECL Kit)

JT96-K002M 250ml*2/Kit
EUR 244.8

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JT96-K002S 100ml*2/Kit
EUR 182.4

T-Pro LumiLong Plus Chemiluminescence Detection Kit (ECL Kit)

JT96-K004M 250ml*2/Kit
EUR 286.8

T-Pro LumiLong Plus Chemiluminescence Detection Kit (ECL Kit)

JT96-K004S 100ml*2/Kit
EUR 204

T-Pro Gel/PCR DNA Purification Maxi Kit (10)

RB94-NEL010 10preps/Kit
EUR 193.2

T-Pro Gel/PCR DNA Purification Mini Kit (100)

RB94-NES100 100preps/Kit
EUR 193.2

T-Pro Gel/PCR DNA Purification Mini Kit (250)

RB94-NES250 250preps/Kit
EUR 266.4

T-Pro Washing buffer in PBS and Tween-20 (10X)

JB09-I003 500ml/BT
EUR 172.8

T-Pro Washing buffer in TBS and Tween-20 (10X)

JB09-I004 500ml/BT
EUR 172.8

T-Pro Phosphate-Buffered Saline (PBS, 10X) for western blot washing

JB09-I001 500ml/BT
EUR 162

T-Pro Tris-Buffered Saline (TBS, 10X) for western blot washing

JB09-I002 500ml/BT
EUR 162

Untransduced T Cells

78170-1 1 vial
EUR 1250
Description: The untransduced T cells are produced by mock lentiviral transduction of human primary CD4+CD8+ T cells. These cells are subjected to comparable manipulations as CAR-T cells: activation, spinoculation (without lentivirus), and expansion. These T cells are meant to be negative controls in experiments using lentivirus-transduced primary CAR-T cells.

Untransduced T Cells

78170-2 5 vials
EUR 3325
Description: The untransduced T cells are produced by mock lentiviral transduction of human primary CD4+CD8+ T cells. These cells are subjected to comparable manipulations as CAR-T cells: activation, spinoculation (without lentivirus), and expansion. These T cells are meant to be negative controls in experiments using lentivirus-transduced primary CAR-T cells.

CD4+ T cells, Negatively Selected (Human)

79752 10 million cells
EUR 395
Description: Cryopreserved vial (10 x 10^6 cells) of CD4+ T cells that were negatively selected from freshly isolated primary human peripheral blood mononuclear cells (PBMCs). The PBMCs came from a healthy donor, and were isolated from whole blood or leukapheresis samples using a Ficoll gradient. Magnetic antibodies to monocytes, granulocytes, CD8+ T cells, gamma/delta T cells and other immune subsets present in PBMCs were then used to purify untouched CD4+ T cells via immunomagnetic separation. Before and after CD4+ T cell isolation, the cells were stained to evaluate purity and viability by flow cytometry. Cells were cryopreserved in CryoStor CS10 cryopreservation medium (Stemcell, #07930) at a controlled rate._x000D_Source
Normal human PBMC from Leukapheresis Sample

CD8+ T cells, Negatively Selected (Human)

79753 10 million cells
EUR 495
Description: Cryopreserved vial (10 x 10^6 cells) of CD8+ T cells that were negatively selected from freshly isolated primary human peripheral blood mononuclear cells (PBMCs). The PBMCs came from a healthy donor, and were isolated from whole blood or leukapheresis samples using a Ficoll gradient. Magnetic antibodies to monocytes, granulocytes, CD4+ T cells, gamma/delta T cells and other immune subsets present in PBMCs were then used to purify untouched CD8+ T cells via immunomagnetic separation. Before and after CD8+ T cell isolation, the cells were stained to evaluate purity and viability by flow cytometry. Cells were cryopreserved in CryoStor CS10 cryopreservation medium (Stemcell, #07930) at a controlled rate._x000D_Source
Normal human PBMC from Leukapheresis Sample

Anti-CD19 CAR-T Cells

78171-1 1 vial
EUR 1595
Description: The anti-CD19 CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-CD19 CAR Lentivirus (CD19 ScFv-CD8-4-1BB-CD3ζ; SIN Vector, BPS Bioscience, #78601). These ready-to use CAR-T cells express an anti-CD19 CAR consisting the ScFv of CD19 (clone FMC63) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains. These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.

Anti-CD19 CAR-T Cells

78171-2 5 vials
EUR 4250
Description: The anti-CD19 CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-CD19 CAR Lentivirus (CD19 ScFv-CD8-4-1BB-CD3ζ; SIN Vector). These ready-to use CAR-T cells express an anti-CD19 CAR consisting the ScFv of CD19 (clone FMC63) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains.These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.

Anti-BCMA CAR-T Cells

78660-1 1 vial
EUR 1595
Description: The anti-BCMA CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-BCMA CAR Lentivirus (BPS Bioscience #78655). These ready-to-use CAR-T cells express an anti-BCMA CAR consisting of the ScFv of BCMA (clone C11D5.3) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains (Figure 1). These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.

Anti-BCMA CAR-T Cells

78660-2 5 vials
EUR 4250
Description: The anti-BCMA CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-BCMA CAR Lentivirus (BPS Bioscience #78655). These ready-to-use CAR-T cells express an anti-BCMA CAR consisting of the ScFv of BCMA (clone C11D5.3) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains (Figure 1). These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.

anti-CD4 T helper cells

502-A-01mg 0,1 mg
EUR 321
Description: anti-CD4 T helper cells

anti-CD4 T helper cells

502-A-1000ug 1000 ug
EUR 1539
Description: anti-CD4 T helper cells

anti-CD4 T helper cells

502-A-100ugvial 100 ug/vial
EUR 150
Description: anti-CD4 T helper cells

Rat Pan T cell antibody (biotin)

61R-T135aBT 200 ug
EUR 878.4
Description: Mouse monoclonal Rat Pan T cell antibody (biotin)

anti-CD8 T cytotoxic/supressor cells

505-A-01mg 0,1 mg
EUR 321
Description: anti-CD8 T cytotoxic/supressor cells

anti-CD8 T cytotoxic/supressor cells

505-A-1000ug 1000 ug
EUR 1539
Description: anti-CD8 T cytotoxic/supressor cells

anti-CD8 T cytotoxic/supressor cells

505-A-100ugvial 100 ug/vial
EUR 150
Description: anti-CD8 T cytotoxic/supressor cells

Human Normal Peripheral Blood CD4+/CD25+ Regulatory T Cells (T reg), Fresh

PBCD4-25-F2M - Ask for price

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC942884-100 100uL
EUR 279.6
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF594 conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC942884-500 500uL
EUR 654
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF594 conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC802884-100 100uL
EUR 279.6
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF680 conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC802884-500 500uL
EUR 654
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF680 conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC702884-100 100uL
EUR 279.6
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF770 conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC702884-500 500uL
EUR 654
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF770 conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC882884-100 100uL
EUR 279.6
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF488A conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC882884-500 500uL
EUR 654
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF488A conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC812884-100 100uL
EUR 279.6
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF680R conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC812884-500 500uL
EUR 654
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF680R conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC402884-100 100uL
EUR 279.6
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF640R conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC402884-500 500uL
EUR 654
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF640R conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC052884-100 100uL
EUR 279.6
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF405M conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC052884-500 500uL
EUR 654
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF405M conjugate, Concentration: 0.1mg/mL

CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) Antibody

BNC042884-100 100uL
EUR 279.6
Description: Primary antibody against CD6 (Negative Marker of T-regulatory Cells) (C6/2884R), CF405S conjugate, Concentration: 0.1mg/mL

On provide, the umbilical twine blood systematic analysis of plasma chosen and transcriptomic biomarkers (procalcitonin, interleukin (IL) -6, IL-10, IP10, CD74 and CX3CR1) associated to sepsis pathophysiology shall be evaluated in the entire keep starting and in the middle of the follow-up and when sepsis might be suspected.

 

Induction of pluripotent stem cells from mouse embryonic and grownup fibroblast cultures by outlined parts.

Differentiatted cells will likely be reprogrammed to an embryonic-like state by swap of nuclear contents into oocytes or by fusion with embryonic stem (ES) cells.

Little is considered parts that induce this reprogramming. Proper right here, we exhibit induction of pluripotent stem cells from mouse embryonic or grownup fibroblasts by introducing 4 parts, Oct3/4, Sox2, c-Myc, and Klf4, beneath ES cell custom circumstances.

Unexpectedly, Nanog was dispensable. These cells, which we designated iPS (induced pluripotent stem) cells, exhibit the morphology and progress properties of ES cells and categorical ES cell marker genes.

Subcutaneous transplantation of iPS cells into nude mice resulted in tumors containing a variety of tissues from all three germ layers. Following injection into blastocysts, iPS cells contributed to mouse embryonic enchancment.

These data exhibit that pluripotent stem cells will likely be instantly generated from fibroblast cultures by the addition of only a few outlined parts.

 

MagIso CD4 Memory T Cell Isolation Kit, Human

WHK-B028 20 tests, 200 tests Ask for price

MagIso CD8 Memory T Cell Isolation Kit, Human

WHK-B026 20 tests, 200 tests Ask for price

Human  Peripheral  Blood  CD14+ Monocytes, Fresh / Positive selection

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Human  Peripheral  Blood  CD14+ Monocytes, Cryopreserved / Positive selection

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SOM02.0 Selected Ion Monitoring 2 Components

CLPS-SOM-ISB 1ML
EUR 118.8

Thymocyte Expressed, Positive Selection Associated 1 (TESPA1) Antibody

abx238602-100ug 100 ug
EUR 661.2

Thymocyte Expressed, Positive Selection Associated 1 (TESPA1) Antibody

20-abx304281
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Thymocyte Expressed, Positive Selection Associated 1 (TESPA1) ELISA Kit

abx383702-96tests 96 tests
EUR 1093.2

Thymocyte Expressed, Positive Selection Associated 1 (TESPA1) Antibody (HRP)

20-abx304282
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Thymocyte Expressed, Positive Selection Associated 1 (TESPA1) Antibody (FITC)

20-abx304283
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Thymocyte Expressed, Positive Selection Associated 1 (TESPA1) Antibody (Biotin)

20-abx304284
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

CD19 Positive Cell Isolation Kit

78564-1 1 x 10^8 Cells
EUR 70
Description: The CD19 Positive Cell Isolation Kit is designed to magnetically separate CD19-expressing-cells from a complex immune cell population. This kit is optimized for the isolation of CD19 positive cells from normal human peripheral blood mononuclear cells (PBMCs). Cells are incubated with the antibody:bead complex and placed on a magnet for quick and easy separation. When placed on the magnet, CD19-positive cells will be immobilized along the side of the tube while undesired CD19-negative cells will remain in suspension for easy removal.

CD19 Positive Cell Isolation Kit

78564-2 1 x 10^9 Cells
EUR 630
Description: The CD19 Positive Cell Isolation Kit is designed to magnetically separate CD19-expressing-cells from a complex immune cell population. This kit is optimized for the isolation of CD19 positive cells from normal human peripheral blood mononuclear cells (PBMCs). Cells are incubated with the antibody:bead complex and placed on a magnet for quick and easy separation. When placed on the magnet, CD19-positive cells will be immobilized along the side of the tube while undesired CD19-negative cells will remain in suspension for easy removal.

4GB USB memory stick

SPE4616 EACH
EUR 48

ICP-MS Memory Test 1

CL-MEM-1 125ML
EUR 483.6

ICP-MS Memory Test 2

CL-MEM-2 125ML
EUR 273.6

CD45RA/CD45RO/CD3/CD4

45RAF245ROPE3PP14A1-50T 50 test
EUR 730.8

Rodwell MP25 USB Memory Logging System

AUT1266 EACH
EUR 1760.4

ICP-MS Set of 2 Memory Test Solutions

CL-MEM-SET EACH
EUR 614.4

Kinesis Rheodyne TitanHP 6 Position 7 Port Selection Valve;Ti;PCB

CHR3701 EACH
EUR 2553.6

CD45RO Antibody (T-cell marker)

V7044-100UG 100 ug
EUR 349.3
Description: CD45RO is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. CD45RO contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. It also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. [RefSeq]

CD45RO Antibody (T-cell marker)

V7044-20UG 20 ug
EUR 153.3
Description: CD45RO is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. CD45RO contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. It also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. [RefSeq]

CD45RO Antibody (T-cell marker)

V7044IHC-7ML 7 ml
EUR 349.3
Description: CD45RO is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. CD45RO contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. It also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. [RefSeq]

CD45RO Antibody (T-cell marker)

V7044SAF-100UG 100 ug
EUR 349.3
Description: CD45RO is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. CD45RO contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. It also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. [RefSeq]

CD45RO Antibody (T-cell marker)

V2416-100UG 100 ug
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2416-20UG 20 ug
EUR 153.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2416SAF-100UG 100 ug
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2419-100UG 100 ug
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2419-20UG 20 ug
EUR 153.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2419IHC-7ML 7 ml
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2419SAF-100UG 100 ug
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2420-100UG 100 ug
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2420-20UG 20 ug
EUR 153.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2420IHC-7ML 7 ml
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2420SAF-100UG 100 ug
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2237-100UG 100 ug
EUR 349.3
Description: This antibody recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45) called CD45RO (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. CD45RO is found on mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. The CD45RO antibody shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, antibody to CD45RO is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2237-20UG 20 ug
EUR 153.3
Description: This antibody recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45) called CD45RO (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. CD45RO is found on mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. The CD45RO antibody shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, antibody to CD45RO is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2237IHC-7ML 7 ml
EUR 349.3
Description: This antibody recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45) called CD45RO (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. CD45RO is found on mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. The CD45RO antibody shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, antibody to CD45RO is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2237SAF-100UG 100 ug
EUR 349.3
Description: This antibody recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45) called CD45RO (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. CD45RO is found on mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. The CD45RO antibody shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, antibody to CD45RO is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

VERO Host Cell Proteins (HCPs) positive control (10 ug/ml)

770-165-PC1 1 ml
EUR 270

AAVS1 Positive Control EGIP 293T Reporter Cell Line

CAS606A-1 1 Vial
EUR 726

Human Complement C3d AssayMax ELISA Kit (Positive Control included)

EC3331-7 96 Well Plate
EUR 572.4

RSV Positive Sample

DAG-H10378 1 ml dry ice
EUR 1326

HEK293 Host Cell Proteins (HEK293-HCP) positive control (10 ug/ml)

740-150-PC1 1 ml
EUR 270

ROS1 positive non-small cell lung NSCLC cancer tissue array

LC261 each
EUR 360
Description: ROS1 positive non-small cell lung NSCLC cancer tissue array, including pathology grade, TNM, clinical stage, IHC ROS1+ results (FISH on request), 21 cases/26 cores

Human Serum (AB positive)

90-1011 100 ml
EUR 580.8
Description: Pooled Normal Human Serum (AB positive)

CD45RO, T-Cell; Clone UCHL1 Concentrate

A00024-C 1 ml
EUR 600

CD45RO

45ROF-100T 100 test
EUR 665.28

CD45RO

45ROPE-100T 100 test
EUR 684

CD45RO Antibody Cocktail (T-cell marker)

V2421-100UG 100 ug
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody cocktail reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody Cocktail (T-cell marker)

V2421-20UG 20 ug
EUR 153.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody cocktail reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody Cocktail (T-cell marker)

V2421IHC-7ML 7 ml
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody cocktail reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody Cocktail (T-cell marker)

V2421SAF-100UG 100 ug
EUR 349.3
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody cocktail reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antigen (CD45RO/PTPRC) Antibody

abx414184-01mg 0.1 mg
EUR 543.6

CD45RO Antigen (CD45RO/PTPRC) Antibody

abx414746-01mg 0.1 mg
EUR 526.8

CD45RO Antigen (CD45RO/PTPRC) Antibody

abx414747-25ug 25 ug
EUR 326.4

Pichia Pastoris Host Cell Proteins (PP-HCP) positive control (10 ug/ml)

750-155-PC1 1 ml
EUR 270

Human Cell-30 protein lysate for WB positive control for PR12-M r protein (PR) IgG #2

PR12-C 100 ul
EUR 343.2

QPCR Positive Control Kit

M1126-100 each
EUR 483.6

Chinese Hamster Ovary Cell (CHO) host cell Proteins (HCPs) positive control (10 ug/ml)

800-140-PC1 1 ml
EUR 270

Human Cell-18 protein lysate for WB positive control for ERA12-A protein (PR) IgG #2

ERA12-C 100 ul
EUR 343.2

NATtrol EV Positive Control (6 X 0.2 mL)

NATEVPOS-6MC 6 X 0.2 mL
EUR 208

NATtrol SA Positive Control (6 X 0.5 mL)

NATMSSA-6MC 6 X 0.5 mL
EUR 311

NATtrol SA Positive Control  (6 X 0.5 mL)

NATMSSA-6MC-IVD 6 X 0.5 mL
EUR 331

NATtrol EV Positive Control (6 X 0.5 mL)

MDZ055 6 X 0.2 mL
EUR 208

NATtrol SA Positive Control (6 X 0.5 mL)

MDZ061 6 X 0.5 mL
EUR 378.24
Description: Please contact Gentaur in order to receive the datasheet of the product.

Rat Positive Cofactor 4 (PC4) CLIA Kit

abx197523-96tests 96 tests
EUR 990

Rotavirus Positive Sample

DAG-H10377 1 ml dry ice
EUR 1326

Dog Positive Cofactor 4 ELISA kit

E08P0063-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Positive Cofactor 4 ELISA kit

E08P0063-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Positive Cofactor 4 ELISA kit

E08P0063-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

NATtrol HSV 1 & 2 Positive Control (6 x 0.25 mL)

NATHSV-6L 6 x 0.25 mL
EUR 272

NATtrol RSV Positive Control (6 X 0.5 mL)

NATRSV-6C-IVD 6 X 0.5 mL
EUR 242

NATtrol GBS Positive Control (6 x 0.25 mL)

NATSAG-6L 6 x 0.25 mL
EUR 272

NATtrol GBS Positive Control (6 X 0.5 mL)

NATSAG-6MC 6 X 0.5 mL
EUR 313

NATtrol GBS Positive Control (6 x 0.5 mL)

NATSAG-6MC-IVD 6 x 0.5 mL
EUR 333

NATtrol CT/NG/TV Positive Control (6 x 1.0mL)

NATCTNGTV-POS 6 x 1.0mL
EUR 368

Rat Positive Cofactor 4 ELISA kit

E02P0063-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Positive Cofactor 4 ELISA kit

E02P0063-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Positive Cofactor 4 ELISA kit

E02P0063-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

NATtrol RSV Positive Control (6 X 0.5 mL)

MDZ047 6 X 0.5 mL
EUR 278.4
Description: Please contact Gentaur in order to receive the datasheet of the product.

NATtrol GBS Positive Control (6 x 0.5 mL)

MDZ053 6 x 0.5 mL
EUR 378.24
Description: Please contact Gentaur in order to receive the datasheet of the product.

Pig Positive Cofactor 4 ELISA kit

E07P0063-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Positive Cofactor 4 ELISA kit

E07P0063-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Positive Cofactor 4 ELISA kit

E07P0063-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

CD45RA / CD45RO / CD3 / CD4 Antibody (FITC, PE, PerCP, APC)

abx200640-50tests 50 tests
EUR 828

Rat Positive Cofactor 4 (PC4) ELISA Kit

abx255897-96tests 96 tests
EUR 848.4

Pig Positive Cofactor 4 (PC4) ELISA Kit

abx361959-96tests 96 tests
EUR 990

CLIA kit for Rat PC4 (Positive Cofactor 4)

E-CL-R0542 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Rat PC4 (Positive Cofactor 4) in samples from Serum, Plasma, Cell supernatant

Rat PC4(Positive Cofactor 4) ELISA Kit

ER1232 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 18.75pg/ml

NATtrol MRSA Positive Control (6 X 0.5 mL)

NATMRSA-6MC 6 X 0.5 mL
EUR 315

NATtrol MRSA Positive Control  (6 X 0.5 mL)

NATMRSA-6MC-IVD 6 X 0.5 mL
EUR 335

NATtrol RSV Positive Control (6 x 0.5mL)

NATRSV-6C 6 x 0.5mL
EUR 222

NATtrol BV Positive Control (6 X 0.15mL)

NATBVPOS-BD 6 X 0.15mL
EUR 446

NATtrol MRSA Positive Control (6 X 0.5 mL)

MDZ059 6 X 0.5 mL
EUR 378.24
Description: Please contact Gentaur in order to receive the datasheet of the product.

Goat Positive Cofactor 4 ELISA kit

E06P0063-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Positive Cofactor 4 ELISA kit

E06P0063-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Positive Cofactor 4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

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