Prophylactic therapy with human amniotic

March 2023
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Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophages

Prophylactic treatment with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis by the use of immunomodulation by the use of aggregates with peritoneal macrophages

 

Background: No matter newest advances in neonatal care, sepsis stays a critical rationalization for lack of life in neonates. Mesenchymal stem cells derived from quite a few tissues, just like bone marrow, umbilical twine and adipose tissues, has helpful outcomes on grownup sepsis. Although human  a amniotic fluid stem cells (hAFSCs) have properties of mesenchymal stem cells, the efficacy hAFSCs on neonatal sepsis stays to be outlined. This look at objectives to research the therapeutic potential of hAFSCs on neonatal sepsis using a rat model of lipopolysaccharide (LPS) induced sepsis.


Methods: hAFSCs isolated as CD117-positive cells from human amniotic fluid. pet rat three-day-old have been intraperitoneally dealt with with LPS to mimic neonatal sepsis. hAFSCs given each Three hours sooner than or at 0, 3, or 24 hours after publicity to LPS. Serum ranges of inflammatory cytokines, gene expression profiles of the spleen and a lot of organ hurt have been analyzed. hAFSC determined in vivo localization. In vitro LPS stimulation verify is carried out using neonatal rat peritoneal macrophages co-cultured with hAFSCs in cells by contact-dependent / neutral. Immunoregulation throughout the spleen was determined by the usage of DNA microarray analysis.


Outcomes: Prophylactic treatment with hAFSCs improve survival in LPS-treated mice whereas hAFSCs transplant after LPS publicity did not get a response to treatment. Subsequently, pretreatment hAFSC used for all subsequent analysis. elevated ranges of inflammatory cytokines after LPS injection, which was attenuated by pretreatment hAFSC. Furthermore, hurt induced irritation throughout the thoughts, lungs, and liver have been repaired.

hAFSCs collected by peritoneal macrophages and / or transiently accumulates throughout the liver, mesentery, and peritoneum. paracrine parts launched by hAFSCs M1-M2 macrophages induced polarization in cells with contact-independent technique. direct contact between hAFSCs and peritoneal macrophages extra enhanced polarization. spleen microarray analysis confirmed that pretreatment hAFSC cut back the expression of genes involved in apoptosis and irritation after which pressed pulses like receptor 4 signaling pathway.


Conclusions: Prophylactic treatment with hAFSCs improve survival in mice LPS-induced neonatal sepsis. This impression may be mediated by the phenotype change from M1 to M2 in peritoneal macrophages, triggered by hAFSCs in cells by contact-dependent / neutral and subsequent immunomodulation spleen.

 Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophages
Prophylactic treatment with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis by the use of immunomodulation by the use of aggregates with peritoneal macrophages

Endeavor sepsis: sepsis biomarker protocol for locating out neonatal and toddler immune response in malaria-endemic areas

Introduction: Neonatal sepsis outreach all-cause neonatal mortality worldwide and stays a critical burden on the group is low and middle earnings nations. Together with restricted property, endemic morbidity, just like malaria and prematurity, neonatal and toddler predispose to invasive an an infection by altering the neonatal immune response in opposition to the pathogen.

However, good epidemiology, diagnostic and immunological evaluation of neonatal sepsis and impression of being pregnant malaria was on no account completed.


Methods and Analysis: A multicenter potential longitudinal follow-up of 580 infants from starting to a few months in metropolis and suburban Benin will do. At provide, and every week, all kids shall be clinically examined and evaluated for the incidence of sepsis.

Untransduced T Cells

78170-1 1 vial
EUR 1250
Description: The untransduced T cells are produced by mock lentiviral transduction of human primary CD4+CD8+ T cells. These cells are subjected to comparable manipulations as CAR-T cells: activation, spinoculation (without lentivirus), and expansion. These T cells are meant to be negative controls in experiments using lentivirus-transduced primary CAR-T cells.

Untransduced T Cells

78170-2 5 vials
EUR 3325
Description: The untransduced T cells are produced by mock lentiviral transduction of human primary CD4+CD8+ T cells. These cells are subjected to comparable manipulations as CAR-T cells: activation, spinoculation (without lentivirus), and expansion. These T cells are meant to be negative controls in experiments using lentivirus-transduced primary CAR-T cells.

anti-CD3 T-cell

501-A-01mg 0,1 mg
EUR 321
Description: anti-CD3 T-cell

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501-A-1000ug 1000 ug
EUR 1539
Description: anti-CD3 T-cell

CD3, T-Cell; Polyclonal

A20030 2 ml
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CD3, T-Cell; Polyclonal

A00030 6 ml
EUR 255.6

CD3, T-Cell; Polyclonal

A00030-0100 100 ml
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CD3, T-Cell; Polyclonal

A00030.0025 25 ml
EUR 745.2

Rat Pan B Cells antibody

10R-B124a 50 ug
EUR 910.8
Description: Mouse monoclonal Rat Pan B Cells antibody

anti-CD45 RA B-cells, T-cells, NK-cells

516-A-01mg 0,1 mg
EUR 321
Description: anti-CD45 RA B-cells, T-cells, NK-cells

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516-A-1000ug 1000 ug
EUR 1539
Description: anti-CD45 RA B-cells, T-cells, NK-cells

T-Pro Stacking Buffer

JB03-C002 500ml/BT
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JT90-R002 500ml/BT
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502-A-01mg 0,1 mg
EUR 321
Description: anti-CD4 T helper cells

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502-A-1000ug 1000 ug
EUR 1539
Description: anti-CD4 T helper cells

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503-A-01mg 0,1 mg
EUR 321
Description: anti-CD5 All T-cells

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503-A-1000ug 1000 ug
EUR 1539
Description: anti-CD5 All T-cells

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504-A-01mg 0,1 mg
EUR 321
Description: anti-CD7 All T-cells

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504-A-1000ug 1000 ug
EUR 1539
Description: anti-CD7 All T-cells

Anti-CD19 CAR-T Cells

78171-1 1 vial
EUR 1595
Description: The anti-CD19 CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-CD19 CAR Lentivirus (CD19 ScFv-CD8-4-1BB-CD3ζ; SIN Vector, BPS Bioscience, #78601). These ready-to use CAR-T cells express an anti-CD19 CAR consisting the ScFv of CD19 (clone FMC63) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains. These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.

Anti-CD19 CAR-T Cells

78171-2 5 vials
EUR 4250
Description: The anti-CD19 CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-CD19 CAR Lentivirus (CD19 ScFv-CD8-4-1BB-CD3ζ; SIN Vector). These ready-to use CAR-T cells express an anti-CD19 CAR consisting the ScFv of CD19 (clone FMC63) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains.These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.

Anti-BCMA CAR-T Cells

78660-1 1 vial
EUR 1595
Description: The anti-BCMA CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-BCMA CAR Lentivirus (BPS Bioscience #78655). These ready-to-use CAR-T cells express an anti-BCMA CAR consisting of the ScFv of BCMA (clone C11D5.3) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains (Figure 1). These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.

Anti-BCMA CAR-T Cells

78660-2 5 vials
EUR 4250
Description: The anti-BCMA CAR-T cells are produced by high-titer lentiviral transduction of human primary CD4+CD8+ T cells using the anti-BCMA CAR Lentivirus (BPS Bioscience #78655). These ready-to-use CAR-T cells express an anti-BCMA CAR consisting of the ScFv of BCMA (clone C11D5.3) linked to a 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains (Figure 1). These CAR-T cells have been validated using flow cytometry (to determine the CAR expression) and co-culture cytotoxicity assays.

Rat Pan T cell antibody (biotin)

61R-T135aBT 200 ug
EUR 878.4
Description: Mouse monoclonal Rat Pan T cell antibody (biotin)

Pan-Ras Activation Assay Kit, Trial Size

STA-400-T 5 assays
EUR 483.6
Description: Our Ras Activation Assays use visible agarose beads to selectively precipitate the active form of specific Ras protein of interest. The precipitated small GTPase is then detected by Western blot using a target-specific antibody included in the kit. Assays are available to detect specific isoforms H-Ras, K-Ras, and N-Ras, as well as a Pan-Ras assay that detects all three isoforms.

Pan B-Cells (Ig Light Chain) Antibody

abx413491-01mg 0.1 mg
EUR 543.6

T-Pro EZ Gel Solution 8%

JB02-B008M 500ml/BT
EUR 266.4

T-Pro EZ Gel Solution 8%

JB02-B008S 100ml/BT
EUR 162

T-Pro EZ Gel Solution 10%

JB02-B010M 500ml/BT
EUR 266.4

T-Pro EZ Gel Solution 10%

JB02-B010S 100ml/BT
EUR 162

T-Pro EZ Gel Solution 12%

JB02-B012M 500ml/BT
EUR 266.4

T-Pro EZ Gel Solution 12%

JB02-B012S 100ml/BT
EUR 162

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JB02-B015M 500ml/BT
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JB02-B015S 100ml/BT
EUR 162

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JB03-C001 500ml/BT
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JB04-D001 500assay/KIT
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JB08-H001 500ml/BT
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T-Pro Western Blot Stripping Reagent

JB11-K002 500ml/BT
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JT90-R001M 500ml/BT
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JT90-R001S 100ml/BT
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JT90-R005M 500ml/BT
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T-Pro EZ stain Gel solution

JT90-R005S 100ml/BT
EUR 151.2

T-Pro P-Fect Transfection Reagent

JT97-N005M 1.0ml/vial
EUR 266.4

T-Pro Plasmid Mini Kit (100)

RB94-YPD100 100preps/Kit
EUR 193.2

T-Pro Plasmid Mini Kit (250)

RB94-YPD250 250preps/Kit
EUR 266.4

T-Pro Plasmid Midi Kit (20)

RB94-YPI020 20preps/Kit
EUR 255.6

T-Pro Plasmid Maxi Kit (10)

RB94-YPM010 10preps/Kit
EUR 266.4

anti-CD8 T cytotoxic/supressor cells

505-A-01mg 0,1 mg
EUR 321
Description: anti-CD8 T cytotoxic/supressor cells

anti-CD8 T cytotoxic/supressor cells

505-A-1000ug 1000 ug
EUR 1539
Description: anti-CD8 T cytotoxic/supressor cells

CD4+ T cells, Negatively Selected (Human)

79752 10 million cells
EUR 395
Description: Cryopreserved vial (10 x 10^6 cells) of CD4+ T cells that were negatively selected from freshly isolated primary human peripheral blood mononuclear cells (PBMCs). The PBMCs came from a healthy donor, and were isolated from whole blood or leukapheresis samples using a Ficoll gradient. Magnetic antibodies to monocytes, granulocytes, CD8+ T cells, gamma/delta T cells and other immune subsets present in PBMCs were then used to purify untouched CD4+ T cells via immunomagnetic separation. Before and after CD4+ T cell isolation, the cells were stained to evaluate purity and viability by flow cytometry. Cells were cryopreserved in CryoStor CS10 cryopreservation medium (Stemcell, #07930) at a controlled rate._x000D_Source
Normal human PBMC from Leukapheresis Sample

CD8+ T cells, Negatively Selected (Human)

79753 10 million cells
EUR 495
Description: Cryopreserved vial (10 x 10^6 cells) of CD8+ T cells that were negatively selected from freshly isolated primary human peripheral blood mononuclear cells (PBMCs). The PBMCs came from a healthy donor, and were isolated from whole blood or leukapheresis samples using a Ficoll gradient. Magnetic antibodies to monocytes, granulocytes, CD4+ T cells, gamma/delta T cells and other immune subsets present in PBMCs were then used to purify untouched CD8+ T cells via immunomagnetic separation. Before and after CD8+ T cell isolation, the cells were stained to evaluate purity and viability by flow cytometry. Cells were cryopreserved in CryoStor CS10 cryopreservation medium (Stemcell, #07930) at a controlled rate._x000D_Source
Normal human PBMC from Leukapheresis Sample

Anti-Guinea pig pan T-cell antibody

STJ16100972 1 mg
EUR 674.4

Pan B-Cells (Ig Light Chain) Antibody (FITC)

abx413490-01mg 0.1 mg
EUR 777.6

Pan B-Cells (Ig Light Chain) Antibody (RPE)

abx413492-100tests 100 tests
EUR 861.6

T-Pro BCA Protein Assay Reagent A

JB04-D001A 500ml/BT
EUR 204

T-Pro BCA Protein Assay Reagent B

JB04-D001B 12ml/BT
EUR 140.4

T-Pro Bradford Protein Assay kit(1X)

JB04-D002 500ml/BT
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T-Pro Fast Blocking Buffer (in PBS)

JK92-W001 500ml/BT
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T-Pro Fast Blocking Buffer (in TBS)

JK92-W002 500ml/BT
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T-Pro Genomic DNA Midi Kit (20)

RB94-NGM020 20preps/kit
EUR 266.4

T-Pro Genomic DNA Mini Kit (100)

RB94-NGS100 100preps/kit
EUR 255.6

Testosterone (T) ELISA Kit

DLR-T-Ge-48T 48T
EUR 562.8
Description: A competitive inhibition quantitative ELISA assay kit for detection of Testosterone (T) in samples from serum, plasma, urine or other biological fluids.

Testosterone (T) ELISA Kit

DLR-T-Ge-96T 96T
EUR 729.6
Description: A competitive inhibition quantitative ELISA assay kit for detection of Testosterone (T) in samples from serum, plasma, urine or other biological fluids.

T-Pro Laemmli (SDS sample) Reagent (reducing 4X)

JB06-F002 10ml/BT
EUR 151.2

T-Pro Tris-Glycine-SDS running buffer (10X)

JB07-G001 500ml/BT
EUR 162

T-Pro Tris-Glycine-Native running buffer (10X)

JB07-G002 500ml/BT
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T-Pro Semi Dry Transfer Blotting buffer (10X)

JB08-H002 500ml/BT
EUR 172.8

T-Pro Protein Free Blocking Buffer (in PBS)

JK92-W003 500ml/BT
EUR 224.4

T-Pro Protein Free Blocking Buffer (in TBS)

JK92-W004 500ml/BT
EUR 224.4

T-Pro Nonliposomal Transfection Reagent I (NTR I)

JT97-N001M 1.0ml/vial
EUR 224.4

T-Pro Nonliposomal Transfection Reagent II (NTR II)

JT97-N002M 1.0ml/vial
EUR 244.8

T-Pro Nonliposomal Transfection Reagent III (NTR III)

JT97-N006M 1.0ml/vial
EUR 266.4

T-Pro Endotoxin Removal Plasmid Midi kit (25)

RB94-EPI020 20preps/Kit
EUR 297.6

T-Pro Endotoxin Removal Plasmid Maxi kit (10)

RB94-EPM010 10preps/Kit
EUR 318

T-Pro Plant Genomic DNA Midi Kit (20)

RB94-PGM020 20preps/kit
EUR 266.4

T-Pro Plant Genomic DNA Mini Kit (100)

RB94-PGS100 100preps/kit
EUR 266.4

Locking T-Handle

M-CP-111-065-T 1 UNIT
EUR 55
Description: Locking T-Handle

T-Cell Surface Glycoprotein CD3 Epsilon (CD3e) Antibody

20-abx104100
  • EUR 510.00
  • EUR 142.80
  • EUR 693.60
  • EUR 201.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 200 ug
  • 20 ug
  • 50 ug

T-Cell Surface Glycoprotein CD3 Epsilon (CD3E) Antibody

20-abx111480
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

T-Cell Surface Glycoprotein CD3 Epsilon (CD3e) Antibody

20-abx270014
  • EUR 594.00
  • EUR 693.60
  • EUR 343.20
  • EUR 1062.00
  • EUR 444.00
  • 100 tests
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  • 50 tests

T-Cell Surface Glycoprotein CD3 Epsilon (CD3e) Antibody

20-abx174729
  • EUR 393.60
  • EUR 994.80
  • EUR 526.80
  • EUR 184.80
  • EUR 309.60
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Recombinant T-Cell Surface Glycoprotein CD3 Epsilon (CD3e)

4-RPD117Hu01
  • EUR 599.54
  • EUR 283.20
  • EUR 1918.27
  • EUR 719.42
  • EUR 1318.85
  • EUR 476.40
  • EUR 4615.68
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human T-Cell Surface Glycoprotein CD3 Epsilon expressed in: E.coli

Recombinant T-Cell Surface Glycoprotein CD3 Gamma (CD3g)

4-RPD118Hu01
  • EUR 603.84
  • EUR 285.60
  • EUR 1934.40
  • EUR 724.80
  • EUR 1329.60
  • EUR 480.00
  • EUR 4656.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human T-Cell Surface Glycoprotein CD3 Gamma expressed in: E.coli

T-Pro Laemmli (SDS sample) Reagent (non-reducing 4X)

JB06-F003 10ml/BT
EUR 151.2

T-Pro LumiFast Plus Chemiluminescence Detection Kit (ECL Kit)

JT96-K002M 250ml*2/Kit
EUR 244.8

T-Pro LumiFast Plus Chemiluminescence Detection Kit (ECL Kit)

JT96-K002S 100ml*2/Kit
EUR 182.4

T-Pro LumiLong Plus Chemiluminescence Detection Kit (ECL Kit)

JT96-K004M 250ml*2/Kit
EUR 286.8

T-Pro LumiLong Plus Chemiluminescence Detection Kit (ECL Kit)

JT96-K004S 100ml*2/Kit
EUR 204

T-Pro Gel/PCR DNA Purification Maxi Kit (10)

RB94-NEL010 10preps/Kit
EUR 193.2

T-Pro Gel/PCR DNA Purification Mini Kit (100)

RB94-NES100 100preps/Kit
EUR 193.2

On provide, the umbilical twine blood systematic analysis of plasma chosen and transcriptomic biomarkers (procalcitonin, interleukin (IL) -6, IL-10, IP10, CD74 and CX3CR1) associated to sepsis pathophysiology shall be evaluated in the entire keep starting and in the middle of the follow-up and when sepsis might be suspected.

 

Induction of pluripotent stem cells from mouse embryonic and grownup fibroblast cultures by outlined parts.

Differentiatted cells will likely be reprogrammed to an embryonic-like state by swap of nuclear contents into oocytes or by fusion with embryonic stem (ES) cells.

Little is considered parts that induce this reprogramming. Proper right here, we exhibit induction of pluripotent stem cells from mouse embryonic or grownup fibroblasts by introducing 4 parts, Oct3/4, Sox2, c-Myc, and Klf4, beneath ES cell custom circumstances.

Unexpectedly, Nanog was dispensable. These cells, which we designated iPS (induced pluripotent stem) cells, exhibit the morphology and progress properties of ES cells and categorical ES cell marker genes.

Subcutaneous transplantation of iPS cells into nude mice resulted in tumors containing a variety of tissues from all three germ layers. Following injection into blastocysts, iPS cells contributed to mouse embryonic enchancment.

These data exhibit that pluripotent stem cells will likely be instantly generated from fibroblast cultures by the addition of only a few outlined parts.

 

anti-CD4 T helper cells

502-A-1000ug 1000 ug
EUR 1539
Description: anti-CD4 T helper cells

CD45RA/CD45RO/CD3/CD4

45RAF245ROPE3PP14A1-50T 50 test
EUR 730.8

MagIso CD8 Memory T Cell Isolation Kit, Human

WHK-B026 20 tests, 200 tests Ask for price

CD45RO Antibody (T-cell marker)

V2419IHC-7ML 7 ml
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2419SAF-100UG 100 ug
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2420-100UG 100 ug
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2420-20UG 20 ug
EUR 219
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2420IHC-7ML 7 ml
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2420SAF-100UG 100 ug
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V7044-100UG 100 ug
EUR 499
Description: CD45RO is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. CD45RO contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. It also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. [RefSeq]

CD45RO Antibody (T-cell marker)

V7044-20UG 20 ug
EUR 219
Description: CD45RO is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. CD45RO contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. It also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. [RefSeq]

CD45RO Antibody (T-cell marker)

V7044IHC-7ML 7 ml
EUR 499
Description: CD45RO is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. CD45RO contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. It also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. [RefSeq]

CD45RO Antibody (T-cell marker)

V7044SAF-100UG 100 ug
EUR 499
Description: CD45RO is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. CD45RO contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. It has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. It also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. [RefSeq]

CD45RO Antibody (T-cell marker)

V2237-100UG 100 ug
EUR 499
Description: This antibody recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45) called CD45RO (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. CD45RO is found on mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. The CD45RO antibody shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, antibody to CD45RO is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2237-20UG 20 ug
EUR 219
Description: This antibody recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45) called CD45RO (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. CD45RO is found on mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. The CD45RO antibody shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, antibody to CD45RO is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2237IHC-7ML 7 ml
EUR 499
Description: This antibody recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45) called CD45RO (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. CD45RO is found on mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. The CD45RO antibody shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, antibody to CD45RO is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2237SAF-100UG 100 ug
EUR 499
Description: This antibody recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45) called CD45RO (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. CD45RO is found on mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. The CD45RO antibody shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, antibody to CD45RO is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2416-100UG 100 ug
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2416-20UG 20 ug
EUR 219
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2416SAF-100UG 100 ug
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2419-100UG 100 ug
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody (T-cell marker)

V2419-20UG 20 ug
EUR 219
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-10 each Ask for price

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-20 each Ask for price

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-30 each Ask for price

Human CD3+ T Cells (Pan T Cells), Cryopreserved

M1299-40 each Ask for price

Untransduced T Cells

78170-1 1 vial
EUR 1250
Description: The untransduced T cells are produced by mock lentiviral transduction of human primary CD4+CD8+ T cells. These cells are subjected to comparable manipulations as CAR-T cells: activation, spinoculation (without lentivirus), and expansion. These T cells are meant to be negative controls in experiments using lentivirus-transduced primary CAR-T cells.

Untransduced T Cells

78170-2 5 vials
EUR 3325
Description: The untransduced T cells are produced by mock lentiviral transduction of human primary CD4+CD8+ T cells. These cells are subjected to comparable manipulations as CAR-T cells: activation, spinoculation (without lentivirus), and expansion. These T cells are meant to be negative controls in experiments using lentivirus-transduced primary CAR-T cells.

CD45RO, T-Cell; Clone UCHL1 Concentrate

A00024-C 1 ml
EUR 600

CD45RO Antibody Cocktail (T-cell marker)

V2421-100UG 100 ug
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody cocktail reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody Cocktail (T-cell marker)

V2421-20UG 20 ug
EUR 219
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody cocktail reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody Cocktail (T-cell marker)

V2421IHC-7ML 7 ml
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody cocktail reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

CD45RO Antibody Cocktail (T-cell marker)

V2421SAF-100UG 100 ug
EUR 499
Description: Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody cocktail reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx159398
  • EUR 326.40
  • EUR 276.00
  • 100 ug
  • 50 ug

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx159399-100ul 100 ul
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx159400-100ul 100 ul
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx159401-100ul 100 ul
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx159402-100ul 100 ul
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx159403-100ul 100 ul
EUR 526.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx159404-100ul 100 ul
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx159405-100ul 100 ul
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx159406-100ul 100 ul
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx137099
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx139124-01mg 0.1 mg
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx139125-01mg 0.1 mg
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx139126-01mg 0.1 mg
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx139127-01mg 0.1 mg
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx140007-01mg 0.1 mg
EUR 343.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx140008-01mg 0.1 mg
EUR 343.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx140009-01mg 0.1 mg
EUR 343.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx140102-01mg 0.1 mg
EUR 376.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx140341-01mg 0.1 mg
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx140432-01mg 0.1 mg
EUR 427.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx134635
  • EUR 427.20
  • EUR 678.00
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx134645
  • EUR 427.20
  • EUR 678.00
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx134646
  • EUR 427.20
  • EUR 678.00
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx146722-100ug 100 ug
EUR 526.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx146728-100ug 100 ug
EUR 526.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx000694
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx001304
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx009476
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx125313
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx111482
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx012383-100ul 100 ul
EUR 493.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx015800-100ul 100 ul
EUR 493.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx019049-100ug 100 ug
EUR 410.4

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx021410-02mg 0.2 mg
EUR 886.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx028455-400ul 400 ul
EUR 627.6

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx028455-80l 80 µl
EUR 343.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx028456-400ul 400 ul
EUR 661.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx028456-80l 80 µl
EUR 385.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx200030-100ug 100 ug
EUR 393.6

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx200854
  • EUR 326.40
  • EUR 493.20
  • 100 ug
  • 500 ug

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx320336
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

T-Cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx242941
  • EUR 560.40
  • EUR 393.60
  • 100 ul
  • 50 ul

T-cell Surface Glycoprotein CD4 (CD4) Antibody

20-abx326208
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx413138-01mg 0.1 mg
EUR 526.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx413139-025mg 0.25 mg
EUR 678

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx413254-01mg 0.1 mg
EUR 543.6

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx413340-025mg 0.25 mg
EUR 678

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx413341-05mg 0.5 mg
EUR 994.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx413342-01mg 0.1 mg
EUR 526.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx413343-25ug 25 ug
EUR 326.4

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx413612-2ml 2 ml
EUR 727.2

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx413766-01mg 0.1 mg
EUR 610.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx413842-01mg 0.1 mg
EUR 543.6

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414255-025mg 0.25 mg
EUR 710.4

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414488-025mg 0.25 mg
EUR 678

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414492-25ug 25 ug
EUR 326.4

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414713-025mg 0.25 mg
EUR 678

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414714-1mg 1 mg
EUR 994.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414765-025mg 0.25 mg
EUR 678

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414766-05mg 0.5 mg
EUR 994.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414768-01mg 0.1 mg
EUR 526.8

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414771-25ug 25 ug
EUR 326.4

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414950-02mg 0.2 mg
EUR 678

T-cell Surface Glycoprotein CD4 (CD4) Antibody

abx414951-25ug 25 ug
EUR 326.4

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